Compile Data Set for Download or QSAR
maximum 50k data
Found 243 for UniProtKB: P19320
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105195(4-(4-Pyrazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-2...)
Affinity DataIC50:  5nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105164(4-(4-Thiophen-2-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105151(4-(4-Vinyl-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50: >6nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced VCAM-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced VCAM-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105178(4-(4-Iodo-phenoxy)-thieno[2,3-c]pyridine-2-carboxy...)
Affinity DataIC50: >10nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260669(US9533985, 57)
Affinity DataIC50:  13nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105205(4-(4-Imidazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260666(US9533985, 54)
Affinity DataIC50:  18nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105201(4-(4-Imidazol-1-yl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced VCAM-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory potency compared to PMA induced VCAM-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory potency compared to PMA induced VCAM-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260671(US9533985, 59)
Affinity DataIC50:  22nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260683(US9533985, 71)
Affinity DataIC50:  22nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105185(4-(4-Methoxymethyl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105182(4-(4-Methoxymethyl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50: >24nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory potency compared to TNF-alpha induced VCAM-1 in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260681(US9533985, 69)
Affinity DataIC50:  31nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260667(US9533985, 55)
Affinity DataIC50:  45nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105162(4-(4-Bromo-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  48nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260654(US9533985, 42)
Affinity DataIC50:  52nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260660(US9533985, 48)
Affinity DataIC50:  54nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105173(4-(4-Amino-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  64nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105159(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory potency compared to IL-1beta induced VCAM-1 expression in human endothelial cells (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105209(4-[4-(1-Hydroxymethyl-cyclopropyl)-phenoxy]-thieno...)
Affinity DataIC50:  74nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105202(4-(Biphenyl-4-yloxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50:  79nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105215(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  85nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105197(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  91nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105161(4-(4-Isopropyl-phenoxy)-thieno[2,3-c]pyridine-2-ca...)
Affinity DataIC50: >100nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105222(4-(4-Trifluoromethyl-phenoxy)-thieno[2,3-c]pyridin...)
Affinity DataIC50: >100nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098490(4-(4-Trifluoromethyl-phenylsulfanyl)-thieno[2,3-c]...)
Affinity DataIC50: >100nMAssay Description:In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260674(US9533985, 62)
Affinity DataIC50:  100nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260680(US9533985, 68)
Affinity DataIC50:  120nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105156(4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105152(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50:  130nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260653(US9533985, 41)
Affinity DataIC50:  130nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105221(4-(4-Ethyl-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)
Affinity DataIC50:  140nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105191(4-[4-(3-Morpholin-4-yl-3-oxo-propenyl)-phenoxy]-th...)
Affinity DataIC50: >140nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260651(US9533985, 39)
Affinity DataIC50:  140nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260673(US9533985, 61)
Affinity DataIC50:  150nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260689(US9533985, 77)
Affinity DataIC50:  150nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105166(4-(4-Fluoro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)
Affinity DataIC50: >153nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260668(US9533985, 56)
Affinity DataIC50:  160nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260656(US9533985, 44)
Affinity DataIC50:  160nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105175(4-(4-{2-[2-(2-Ethoxy-ethoxy)-ethoxy]-1,1-difluoro-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029632(3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxy...)
Affinity DataIC50:  175nMAssay Description:In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105177(4-[4-(3-Methyl-3H-imidazol-4-yl)-phenoxy]-thieno[2...)
Affinity DataIC50: >180nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM260662(US9533985, 50)
Affinity DataIC50:  180nMpH: 9.6 T: 2°CAssay Description:The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105211(4-(4-Hydroxymethyl-phenoxy)-thieno[2,3-c]pyridine-...)
Affinity DataIC50:  191nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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